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SGLT2 inhibitors have a mean BP lowering effect of 3.8 mmHg systolic/1.4 mmHg diastolic compared to placebo, an effect which appears to be largely independent of the baseline BP and HbA1c lowering, and preserved in patients with CKD 2 , 4 , 7

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Despite current limitations in counteracting cancer cachexia due to its complex pathogenesis and lack of targeted agents, BPC157, a pentadecapeptide, shows promising potential as a fundamental agent targeting the signaling processes implicated in cancer cachexia