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Research has characterised MT-1s ability to confer photoprotection through mechanisms operating independently of melanin synthesis , documenting enhanced nucleotide excision repair activity, reduced cyclobutane pyrimidine dimer accumulation following UV challenge, and antioxidant pathway upregulation in MT-1-treated melanocytes and keratinocytes

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This aligns with my clinical experience, where I frequently see a variable response to GLP-1 medications, said Mir Ali, MD, bariatric surgeon and medical director of MemorialCare Surgical Weight Loss Center at Orange Coast Medical Center in Fountain Valley, CA

2025;358(4):e3127